| Abstract |
In this study, we investigated the test of the septum in walnut kernel (Juglans regia L). Walnut septum has been widely used in Iranian traditionally used to treat diabetic patients and other different diseases like skin or colon cancer and acts as an antidiabetic, anti-inflammatory, antioxidant, anti-allergic, antimicrobial, antiviral, cardio protective, and neuroprotective agent etc. Crushing walnuts in the laboratory using a wooden hammer, by braking of walnut fruit separating the Walnut kernel septum membranes. carefully removing the walnut septa. Each walnut septum sample originating from the same tree. The walnut membrane septum was dried by natural method approximately 7 days, in a dark place, in order to remove the moisture initially present. The walnut septum membrane was divided into two parts. In one method the directly walnut septum membrane soak into ethanol and distilled water directly. Another part of Walnut kernel septum membranes was powdered by electric grinder and then The powdered material was soak into ethanol and distilled water. The solvents used were Ethanol and distilled water with different ration, at room temperature with occasionally shaking for 21 days. The solution was holding on in an exceedingly airtight dry, clean and away from light. Afterwards, the mixture was filtered using whatman filter paper and collected the concentrated extract (Walnut Septum Solution) WSS for further evaluation. Obtained extract was stored in a refrigerator for further tests. The evaluation parameter like, Moisture content, Total Ash values, boiling point, Specific gravity, Density, Viscosity, PH, Appearance, HPTLC analysis/HPLC Analysis, in vitro drug release profile of extracted solution and stability studies shows all solutions are under the range. The solution F1 give excellent drug release. With the help of HPLC method, we find the walnut septum membranes solution are having the flavonoids: catechin, rutin, myricetin, luteolin, quercetin, apigenin, and kaempferol were Present. Keywords., Walnut, Juglans regia L. Kernel, Septum, solution
|
